Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:10mg Product Name 1-(Methoxy-d3)-3-methyl-2-nitrobenzene Synonyms CAS
Propargyl-Gly(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Size:10mg Product Name 1-(Methoxy-d3)-3-methyl-2-nitrobenzene Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Propargyl Gly(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The propargyl functional group is widely employed in click chemistry to undergo selective cycloaddition with azides. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. The
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